Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception. Notify your clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Older adults may have higher risk of edema or glucose changes
• Individuals with diabetes or prediabetes require close monitoring
• Use caution in kidney or liver impairment
• Avoid use in individuals with any cancer history unless cleared by oncology

Administration
Inject subcutaneously into the abdomen, thigh, or upper arm. Many clinicians recommend dosing in the evening to align with natural growth hormone patterns. Rotate injection sites. Do not adjust the dose without clinician guidance.

Storage
Refrigerate at 36 to 46 degrees Fahrenheit. Protect from light. Follow pharmacy instructions for reconstitution and beyond-use dates. Do not use if cloudy, discolored, or containing particles.

Monitoring
Clinician may monitor fasting glucose, A1c, IGF-1 levels, weight, blood pressure, fluid retention, symptoms of nerve compression, headaches, and vision changes. Individuals with cancer history may require ongoing surveillance.

Regulatory Note
Neither CJC 1295 nor ipamorelin is FDA-approved for any human use. This combination is compounded and has not been reviewed by the FDA for safety, quality, or effectiveness.

Sermorelin

Overview
Sermorelin is a synthetic growth hormone releasing hormone analog. It was once FDA-approved for pediatric growth hormone deficiency, but the FDA approval was discontinued for commercial reasons. Current formulations are compounded and not FDA-approved. Sermorelin is often used off-label for wellness, anti-aging, and body composition, but long-term safety in adults is not established. It stimulates the growth hormone and IGF-1 pathway and may increase risks in certain individuals.

Do Not Use If
• You have active cancer or an unexplained mass
• You have a history of cancer without oncology clearance
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old unless prescribed for true pediatric growth hormone deficiency by a specialist
• You have had a severe allergic reaction to sermorelin or formulation ingredients

Precautions
Tell your clinician if you have:
• Diabetes, prediabetes, or insulin resistance
• Cardiovascular disease, hypertension, or edema
• Sleep apnea
• Thyroid disorders
• History of migraines, severe headaches, or vision changes
• Liver or kidney impairment
• Autoimmune conditions or immunosuppression
• Any history of cancer
• Use of corticosteroids or other medications that affect growth hormone or IGF-1 activity

Drug Interactions
• Corticosteroids may reduce effectiveness
• Insulin or antidiabetic medications may require dose adjustments
• Other growth hormone related therapies, including growth hormone, GHRH products, GHRP products, and MK-677, may increase risk of excessive IGF-1 activity
• Alcohol may increase dizziness or metabolic stress

Common Side Effects
Injection site redness or swelling, flushing, headache, lightheadedness, mild edema, fatigue, nausea, increased appetite, or sleep changes.

Serious Side Effects
Severe allergic reaction, rapid swelling or shortness of breath, worsening blood sugar control, persistent headaches with vision changes, rapid weight gain, or symptoms suggesting tumor activity in individuals with a history of cancer.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use reliable contraception. Notify your clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for routine use in individuals under 18
• Older adults may have higher risk of edema or glucose changes
• Individuals with diabetes or prediabetes require close monitoring
• Use caution in kidney or liver impairment
• Avoid in individuals with prior cancer unless cleared by oncology

Administration
Inject subcutaneously into the abdomen, thigh, or upper arm. Commonly taken at bedtime to match natural growth hormone patterns. Rotate injection sites. Do not change the dose without guidance from your clinician.

Storage
Refrigerate at 36 to 46 degrees Fahrenheit. Protect from light. Follow pharmacy instructions for reconstitution and beyond-use dates. Do not use if the solution is cloudy, discolored, or contains particles.

Monitoring
Clinician may monitor fasting glucose, A1c, IGF-1 levels, weight, blood pressure, edema, headaches, and vision changes. Cancer survivors may require additional surveillance.

Regulatory Note
Sermorelin is no longer an FDA-approved product. All available versions are compounded and not reviewed by the FDA for safety or effectiveness.

IGF-1 LR3

Overview
IGF-1 LR3 is a synthetic analog of insulin-like growth factor 1 with an extended activity profile. It is not FDA-approved for any indication. All human use is compounded and considered investigational. IGF-1 LR3 activates the IGF-1 pathway, which is involved in cell growth and metabolism, and may increase risk in certain individuals.

Do Not Use If
• You have active cancer or an unexplained mass
• You have a history of cancer without oncology clearance
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have had a severe allergic reaction to IGF-1 products or peptide formulations

Precautions
Tell your clinician if you have:
• Diabetes, prediabetes, low blood sugar episodes, or insulin resistance
• Cardiovascular disease, hypertension, or edema
• Thyroid disorders
• History of migraines, vision changes, or intracranial pressure problems
• History of seizures
• Kidney or liver impairment
• Autoimmune disorders or immunosuppression
• Any history of cancer
• Use of insulin, antidiabetic medications, growth hormone, or other peptides that influence the IGF-1 pathway

Drug Interactions
• Insulin or other antidiabetic medications may increase risk of low blood sugar
• Corticosteroids may reduce effectiveness
• Growth hormone, GHRH products, GHRP products, and MK-677 may increase risk of excessive IGF-1 activity
• Alcohol may worsen dizziness or affect glucose regulation

Common Side Effects
Injection site redness or swelling, headache, fatigue, dizziness, mild edema, increased appetite, muscle discomfort, or joint pain.

Serious Side Effects
Severe low blood sugar, severe allergic reaction, vision changes, persistent headaches, significant swelling, shortness of breath, rapid weight gain, or signs suggesting tumor activity in individuals with a cancer history.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception. Inform your clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Older adults may be at higher risk of edema or glucose instability
• Individuals with diabetes or prediabetes require close glucose monitoring
• Avoid use in individuals with history of cancer unless cleared by oncology
• Use caution in kidney or liver impairment

Administration
Inject subcutaneously into abdomen, thigh, or upper arm. Follow exact dosing from your clinician. Rotate injection sites. Do not change dose independently.

Storage
Refrigerate at 36 to 46 degrees Fahrenheit. Protect from light. Follow pharmacy reconstitution and beyond-use instructions. Do not use if cloudy, discolored, or containing particles.

Monitoring
Clinician may monitor fasting glucose, A1c, IGF-1 serum levels, weight, blood pressure, edema, neurologic symptoms, and any vision changes. Cancer surveillance may be necessary for individuals with prior history.

Regulatory Note
IGF-1 LR3 is not FDA-approved. All use is compounded and investigational. Safety and effectiveness have not been reviewed by the FDA.

BPC-157

Overview
BPC‑157 is a synthetic peptide derived from a naturally occurring body protection compound. It is used in compounded form for tissue healing, joint and tendon support, gastrointestinal support, and wellness purposes. It is not FDA-approved for any indication. Safety and long-term effectiveness in humans are limited. BPC‑157 may be combined with other peptides such as TB‑500, GHK‑Cu, or KPV; the same precautions generally apply for combination therapies.

Do Not Use If

• Pregnant, planning pregnancy, or breastfeeding
  
  
• Under 18 years old
  
  
• Active cancer or history of malignancy without oncology clearance
  
  
• Known hypersensitivity to BPC‑157 or excipients
  
  

Precautions
Tell your clinician if you have:

• Autoimmune or chronic inflammatory disease
  
  
• Cardiovascular disease, hypertension, or edema
  
  
• History of blood clots or vascular disorders
  
  
• Liver or kidney impairment
  
  
• Gastrointestinal disorders or prior GI surgery
  
  
• Use of other peptides or biologics
  
  
• History of cancer or precancerous lesions
  
  

Drug Interactions

• Data are limited. Disclose all medications, especially anticoagulants, immunosuppressants, corticosteroids, or other peptide therapies.
  
  

Common Side Effects
Injection site redness or irritation, mild swelling, headache, fatigue, dizziness, transient nausea, or mild flu-like symptoms.

Serious Side Effects
Severe allergic reaction, rapid swelling, chest pain, shortness of breath, neurological changes, or unexpected vascular events. Seek immediate medical care if these occur.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception and notify their clinician immediately if pregnancy occurs.

Special Populations

• Not recommended for individuals under 18
  
  
• Use caution in older adults, particularly with vascular or fluid retention risks
  
  
• Avoid in individuals with cancer history unless cleared by oncology
  
  
• Use caution in liver or kidney impairment
  
  
• Monitor copper levels if used in blends containing GHK‑Cu
  
  

Administration
Inject subcutaneously into the abdomen, thigh, or upper arm as directed. Rotate injection sites to minimize irritation. Follow all dosing instructions and do not adjust the dose independently.

Storage
Refrigerate at 36–46°F. Protect from light. Follow pharmacy instructions for reconstitution and beyond-use dates. Do not use if cloudy, discolored, or containing particles.

Monitoring
Clinician may monitor inflammatory markers, vascular status, weight, blood pressure, symptom progression, and any unexpected adverse effects. Cancer history may require additional surveillance.

Regulatory Note
BPC‑157, including compounded blends with TB‑500, GHK‑Cu, or KPV, is not FDA-approved. Safety, purity, and effectiveness have not been evaluated by the FDA.

‍

TB-500

Overview
TB-500 is a synthetic version of a portion of thymosin beta 4, a peptide involved in cellular repair and tissue regeneration. It is used in compounded form for recovery, injury healing, and performance purposes. TB-500 is not FDA-approved for any indication. Human clinical data are limited, and all use is considered investigational.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have active cancer or a history of cancer without oncology clearance
• You have had a severe allergic reaction to peptide products or formulation ingredients

Precautions
Tell your clinician if you have:
• Autoimmune disorders or chronic inflammatory disease
• Cardiovascular disease, hypertension, or edema
• History of blood clots, stroke, or vascular disease
• Liver or kidney impairment
• Immunosuppression or long-term steroid use
• GI disorders or prior GI surgery
• Any history of cancer or precancerous lesions

Drug Interactions
Human data are limited. Inform your clinician about all medications and supplements, especially:
• Anticoagulants or antiplatelet drugs
• Immunosuppressants
• Corticosteroids
• Other investigational peptides or biologics

Common Side Effects
Injection site redness or irritation, mild swelling, headache, fatigue, dizziness, or transient flu-like feelings.

Serious Side Effects
Severe allergic reaction, new or worsening swelling, chest pain, shortness of breath, severe dizziness, or symptoms suggesting a vascular event. Seek medical attention if serious symptoms occur.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception while taking peptide therapies. Notify your clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Use caution in older adults, especially with cardiovascular or clotting risk
• Use caution in liver or kidney impairment
• Avoid use in individuals with cancer history unless cleared by oncology

Administration
Inject subcutaneously into the abdomen, thigh, or upper arm as instructed by your clinician. Rotate injection sites to reduce irritation. Do not change the dose without medical guidance.

Storage
Refrigerate at 36 to 46 degrees Fahrenheit. Protect from light. Follow pharmacy instructions regarding reconstitution and beyond-use dates. Do not use if cloudy, discolored, or containing particles.

Monitoring
Clinician may monitor symptoms, blood pressure, signs of swelling, vascular status, inflammatory markers if relevant, and any unexpected adverse reactions.

Regulatory Note
TB-500 is not FDA-approved. All use is compounded and investigational. The FDA has not reviewed TB-500 for safety, purity, or effectiveness.

MOTS-C

Overview
MOTS-C is a mitochondrial-derived peptide involved in cellular energy regulation, metabolic signaling, and stress response. All human use is off-label, investigational, and not FDA-approved. Data from controlled human trials are limited, and long-term safety is not established. MOTS-C may affect glucose metabolism, mitochondrial activity, and inflammatory pathways.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have active cancer or a history of cancer without oncology clearance
• You have had a severe allergic reaction to peptide formulations

Precautions
Tell your clinician if you have:
• Diabetes, prediabetes, or fluctuating blood sugar levels
• Cardiovascular disease, hypertension, or edema
• Thyroid disorders or adrenal disorders
• Liver or kidney impairment
• Autoimmune disease or chronic inflammatory conditions
• History of chronic fatigue or mitochondrial disorders
• Any history of cancer or precancerous lesions
• Immunosuppression or long-term steroid use
• Use of other peptides that influence metabolism or mitochondrial activity

Drug Interactions
Human data are limited. Disclose all medications and supplements, especially:
• Insulin or other antidiabetic medications
• Thyroid medication
• Corticosteroids
• Immunosuppressants
• Stimulants or energy-modulating supplements
• Other metabolic or mitochondrial peptides

Common Side Effects
Mild injection site redness or irritation, temporary fatigue, headache, lightheadedness, nausea, or mild shifts in appetite or energy levels.

Serious Side Effects
Severe allergic reaction, significant dizziness, rapid swelling, chest pain, severe shortness of breath, persistent abdominal pain, or marked changes in blood sugar. Seek immediate care if serious symptoms occur.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception while taking peptide therapies. Notify your clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Older adults may be more sensitive to metabolic changes
• Individuals with diabetes or prediabetes require close glucose monitoring
• Avoid use in individuals with cancer history unless cleared by oncology
• Use caution in kidney or liver impairment

Administration
Inject subcutaneously into the abdomen, thigh, or upper arm as directed by your clinician. Rotate injection sites. Follow the dosing schedule exactly and do not adjust the dose on your own.

Storage
Refrigerate at 36 to 46 degrees Fahrenheit. Protect from light. Follow pharmacy instructions for reconstitution and beyond-use dating. Do not use if cloudy, discolored, or containing particles.

Monitoring
Clinician may monitor fasting glucose, A1c, metabolic markers, energy levels, weight, blood pressure, and any neurologic or cardiovascular symptoms. Individuals with cancer history may require increased surveillance.

Regulatory Note
MOTS-C is not FDA-approved. It is only available through compounding pharmacies and has not been reviewed by the FDA for safety, purity, or effectiveness.

5-Amino-1MQ

Overview
5-Amino-1MQ is an investigational small molecule that targets the enzyme NNMT, which may influence metabolism, adipose activity, and cellular energy pathways. It is not FDA-approved for any indication. Human research is limited, and long-term safety is unknown. All use is considered off-label and experimental.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have active cancer or a history of cancer without oncology clearance
• You have had a severe allergic reaction to this compound or formulation ingredients

Precautions
Tell your clinician if you have:
• Cardiovascular disease, hypertension, or arrhythmias
• Diabetes, prediabetes, or unstable blood sugar
• Thyroid disorders
• Kidney or liver impairment
• Autoimmune conditions or chronic inflammatory conditions
• History of neurologic symptoms, severe headaches, or dizziness
• Any history of cancer or precancerous lesions
• Use of stimulants or appetite suppressants
• Use of other metabolic peptides or fat loss agents

Drug Interactions
Human data are limited. Inform your clinician if you take:
• Stimulants or thermogenic supplements
• Antidiabetic medications
• Thyroid medications
• Weight-loss medications or appetite suppressants
• Hormonal therapies
• Immunosuppressants or corticosteroids
• Any other metabolic or mitochondrial treatments

Common Side Effects
Nausea, decreased appetite, dry mouth, mild headache, temporary fatigue or restlessness, mild GI discomfort, or slight changes in energy levels.

Serious Side Effects
Severe allergic reaction, chest pain, irregular heartbeat, severe dizziness, fainting, shortness of breath, marked changes in blood pressure, or significant mood or neurologic changes. Seek immediate medical care if these occur.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception while taking this therapy. Notify your clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Use caution in older adults, especially with cardiovascular conditions
• Individuals with diabetes or prediabetes may require glucose monitoring
• Avoid in individuals with cancer history unless cleared by oncology
• Use caution in kidney or liver impairment

Administration
Typically taken orally as directed by your clinician. Do not exceed recommended dosage. Avoid combining with stimulants or weight-loss agents unless approved by your provider.

Storage
Store at room temperature away from heat, moisture, and direct sunlight. Keep out of reach of children and pets.

Monitoring
Clinician may monitor blood pressure, heart rate, metabolic markers, fasting glucose, energy levels, and any cardiovascular or neurologic symptoms.

Regulatory Note
5-Amino-1MQ is not FDA-approved. It is a compounded investigational product and has not been reviewed by the FDA for safety, purity, or effectiveness.

GAC (Glutamine, Arginine, Carnitine)

Overview
GAC is a compounded injectable blend that commonly includes glutamine, arginine, and carnitine. It is used for metabolic support, energy enhancement, recovery, and fat metabolism. GAC injections are not FDA-approved for any indication. Human data vary depending on formulation, and long-term safety has not been fully established. Each component may influence nitric oxide production, ammonia metabolism, and fatty acid transport.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have had a severe allergic reaction to any amino acid injections
• You have active cancer unless cleared by oncology
• You have a history of severe kidney disease, urea cycle disorders, or hyperammonemia

Precautions
Tell your clinician if you have:
• Cardiovascular disease, uncontrolled hypertension, or arrhythmias
• Liver or kidney impairment
• Diabetes or unstable blood sugar
• Thyroid disorders
• History of migraines or nitric oxide sensitivity
• GI disorders such as severe IBS or prior GI surgery
• Autoimmune disease or chronic inflammatory conditions
• Prior reactions to amino acid or carnitine injections
• Use of stimulants, pre-workout supplements, or nitrate-containing products

Drug Interactions
Inform your clinician about all medications and supplements, especially:
• Blood pressure medications
• Nitrates or PDE-5 inhibitors
• Anticoagulants or antiplatelet medications
• Thyroid medications
• Stimulants or thermogenic supplements
• Carnitine, amino acid, or nitric oxide supplements
• Insulin or antidiabetic medications

Common Side Effects
Mild injection site redness or discomfort, flushing, warmth, headache, lightheadedness, mild nausea, or temporary increase in energy or heart rate.

Serious Side Effects
Severe allergic reaction, chest pain, irregular heartbeat, shortness of breath, severe dizziness or fainting, intense headaches, or neurologic symptoms. Seek medical care immediately if these occur.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use appropriate contraception. Notify your clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Use caution in older adults with cardiovascular conditions
• Use caution in individuals with kidney or liver disease
• Avoid use in individuals with seizure history or metabolic disorders
• Cancer history may require oncology clearance

Administration
Inject subcutaneously into the abdomen, thigh, or upper arm as directed by your clinician. Rotate injection sites. Follow dosing instructions carefully and do not self-adjust.

Storage
Refrigerate at 36 to 46 degrees Fahrenheit or store at room temperature if permitted by your pharmacy. Protect from light. Do not use if the solution is cloudy, discolored, or contains particles.

Monitoring
Clinician may monitor blood pressure, heart rate, kidney and liver function, metabolic markers, glucose levels if applicable, and any neurologic or cardiovascular responses.

Regulatory Note
GAC is not FDA-approved. All formulations are compounded and vary by pharmacy. The FDA has not reviewed GAC injections for safety, purity, or effectiveness.

NAD+ (Nicotinamide Adenine Dinucleotide)

Overview
NAD+ is a coenzyme involved in cellular energy production, mitochondrial function, and metabolic signaling. Injectable NAD+ is used for wellness, recovery, cognitive support, and metabolic enhancement. NAD+ injections are not FDA-approved for any indication. Human evidence varies widely, and long-term safety is not fully established.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have had a severe allergic reaction to NAD+ or injectable vitamin formulations
• You have active cancer unless cleared by oncology
• You have uncontrolled cardiovascular disease or severe autonomic instability

Precautions
Tell your clinician if you have:
• Cardiovascular disease, arrhythmias, or uncontrolled hypertension
• Thyroid disorders
• Liver or kidney impairment
• Diabetes or unstable blood sugar
• Migraines or chronic headaches
• Mitochondrial disorders
• Autoimmune disease or chronic inflammatory conditions
• History of dizziness, flushing, or vasovagal reactions with injections
• Use of stimulants, pre-workout supplements, or energy-boosting compounds

Drug Interactions
Inform your clinician about all medications and supplements, especially:
• Stimulants or thermogenic supplements
• Blood pressure or heart rate medications
• Thyroid medications
• Antidiabetic medications
• Other injectable vitamins or metabolic therapies
• Alcohol or substances that affect autonomic regulation

Common Side Effects
Flushing, warmth, headache, lightheadedness, mild nausea, chest tightness, fatigue, or increased sensitivity during injection. These effects are often linked to infusion or injection speed.

Serious Side Effects
Severe allergic reaction, chest pain, irregular heartbeat, severe dizziness or fainting, shortness of breath, persistent vomiting, or neurologic symptoms. Seek immediate medical care if these occur.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception while receiving NAD+. Notify your clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Older adults may be more sensitive to changes in blood pressure or heart rate
• Individuals with diabetes or thyroid conditions may need metabolic monitoring
• Avoid use in individuals with cancer history unless cleared by oncology
• Use caution in liver or kidney impairment

Administration
Administered by subcutaneous injection, intramuscular injection, or sometimes slow IV infusion depending on clinician instruction. Injection speed may need to be slow to minimize flushing or nausea. Do not change the dose or rate without medical guidance.

Storage
Store according to pharmacy instructions, typically refrigerated at 36 to 46 degrees Fahrenheit or at room temperature if specifically allowed. Protect from light. Do not use if the solution is cloudy, discolored, or contains particles.

Monitoring
Clinician may monitor blood pressure, heart rate, symptom response, metabolic markers, hydration status, and any neurologic or cardiovascular symptoms during and after administration.

Regulatory Note
NAD+ injections are not FDA-approved. All formulations are compounded and vary by pharmacy. The FDA has not evaluated NAD+ for safety, purity, or effectiveness.

Vitamin B12 (Injectable)

Overview
Injectable vitamin B12 (commonly methylcobalamin or hydroxocobalamin) is used for energy support, deficiency treatment, metabolism, and overall wellness. B12 injections are FDA-approved only for treating true B12 deficiency and certain anemias. All wellness or performance uses are off-label. Safety is generally good, but allergic reactions and cardiovascular or metabolic effects can occur.

Do Not Use If
• You have had a severe allergic reaction to vitamin B12, cobalt, or injectable vitamin formulations
• You have Leber optic neuropathy or a family history of this condition
• You are under 18 years old unless prescribed specifically for deficiency
• You have active cancer unless cleared by oncology (B12 can support cell growth)

Precautions
Tell your clinician if you have:
• Heart disease, arrhythmias, or uncontrolled hypertension
• Kidney or liver impairment
• History of acne or rosacea (B12 may occasionally worsen flare-ups)
• History of polycythemia or elevated red blood cell counts
• GI disorders that affect absorption
• Autoimmune disease or chronic inflammatory conditions
• Use of other injections, vitamins, or metabolic treatments

Drug Interactions
Inform your clinician if you take:
• Metformin
• Proton pump inhibitors
• H2 blockers
• Chloramphenicol
• Potassium supplements
• Other injectable vitamins or metabolic therapies
• Alcohol in significant amounts

Common Side Effects
Injection site redness or soreness, mild headache, nausea, diarrhea, flushing, or a sense of increased energy shortly after injection.

Serious Side Effects
Severe allergic reaction, rapid swelling, difficulty breathing, chest pain, irregular heartbeat, sudden dizziness, or numbness or tingling that worsens. Seek urgent care if these occur.

Pregnancy and Contraception
Vitamin B12 is generally considered safe during pregnancy when medically indicated. For high doses, compounded formulations, or non-deficiency uses, discuss with your clinician before use.

Special Populations
• Children should only receive B12 injections under medical supervision
• Older adults may require additional monitoring for anemia or deficiency markers
• Individuals with acne-prone skin may experience temporary worsening
• Individuals with cancer history should obtain oncology clearance
• Individuals with kidney or liver disease may require adjusted dosing

Administration
Inject intramuscularly or subcutaneously depending on clinician instructions. Rotate injection sites. Do not self-adjust dosing frequency.

Storage
Store at room temperature or as directed by the pharmacy. Protect from excessive heat and light. Do not use if the solution is cloudy or discolored.

Monitoring
Clinician may monitor B12 levels, methylmalonic acid, homocysteine, blood counts, and symptom response, especially if used for deficiency or metabolic support.

Regulatory Note
Only certain B12 injectables are FDA-approved for deficiency treatment. Wellness and performance use is off-label. Compounded formulations vary by pharmacy and are not FDA-reviewed for safety, purity, or effectiveness.

CoQ10 (Injectable)

Overview
Injectable CoQ10 (ubiquinone or ubiquinol) is used for metabolic support, energy production, antioxidant activity, and cardiovascular wellness. CoQ10 injections are not FDA-approved for any indication. Human safety data for injectable forms are limited. Oral CoQ10 is generally well tolerated, but injectable administration carries additional risks.

Do Not Use If
• You have had a severe allergic reaction to CoQ10 or injectable vitamin formulations
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have active cancer unless cleared by oncology
• You have a known allergy to lipid-based or oil-based injectable carriers (if applicable to your formulation)

Precautions
Tell your clinician if you have:
• Cardiovascular disease, arrhythmias, or uncontrolled hypertension
• Low blood pressure or a history of vasovagal episodes
• Liver or kidney impairment
• Diabetes or glucose instability
• Autoimmune or inflammatory conditions
• History of bleeding disorders
• Use of anticoagulants or antiplatelet medications
• Use of other antioxidant therapies or nutraceuticals

Drug Interactions
Inform your clinician if you take:
• Warfarin or other anticoagulants (CoQ10 may reduce anticoagulant effect)
• Blood pressure medications
• Chemotherapy agents
• Thyroid medications
• Other injectable vitamins or antioxidant therapies
• Diabetes medications

Common Side Effects
Injection site redness or discomfort, mild nausea, headache, dizziness, lightheadedness, temporary change in energy levels, or mild GI upset.

Serious Side Effects
Severe allergic reaction, sudden dizziness or fainting, chest pain, irregular heartbeat, difficulty breathing, severe nausea or vomiting, or uncontrolled bleeding. Seek urgent care if these symptoms occur.

Pregnancy and Contraception
Do not use injectable CoQ10 during pregnancy or breastfeeding. Oral CoQ10 may be permitted only under clinician supervision for specific medical reasons. Individuals who can become pregnant should discuss contraception and notify their clinician if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Older adults may require blood pressure and medication interaction monitoring
• Individuals with clotting disorders or on blood thinners require close medical oversight
• Individuals with cancer history should obtain oncology clearance
• Use caution in kidney or liver impairment

Administration
Inject intramuscularly or subcutaneously depending on clinician instructions. Injection may need to be slow to reduce discomfort. Rotate injection sites. Do not adjust dose or frequency without clinician guidance.

Storage
Store according to pharmacy instructions, typically at room temperature away from heat and light. Do not use if the solution becomes cloudy, separated, or discolored.

Monitoring
Clinician may monitor blood pressure, heart rate, INR or coagulation status if you take anticoagulants, energy levels, symptom response, and any adverse reactions.

Regulatory Note
Injectable CoQ10 is not FDA-approved. All compounded formulations vary by pharmacy. The FDA has not evaluated injectable CoQ10 for safety, purity, or effectiveness.

Phentermine + Topiramate

Overview
Phentermine combined with topiramate is used for chronic weight management. The FDA-approved product is Qsymia. Compounded versions are not FDA-approved and may differ in strength, purity, and release profile. This medication affects appetite, metabolism, and the central nervous system. It carries important safety considerations, especially for cardiovascular, psychiatric, and pregnancy-related risks.

Do Not Use If
• You are pregnant or planning pregnancy
• You have glaucoma
• You have uncontrolled hyperthyroidism
• You have taken an MAOI within the past 14 days
• You have had a severe allergic reaction to phentermine, topiramate, or formulation ingredients
• You have severe cardiovascular disease such as arrhythmias, stroke history, or uncontrolled hypertension

Precautions
Tell your clinician if you have:
• Depression, anxiety, or mood disorders
• History of suicidal thoughts or behaviors
• Seizure disorders or epilepsy
• Kidney stones or metabolic acidosis
• Kidney or liver impairment
• Alcohol use disorder
• Cardiovascular disease or high blood pressure
• Vision problems or history of narrow-angle glaucoma
• Diabetes or blood sugar fluctuations
• Long-term use of central nervous system medications

Drug Interactions
Inform your clinician if you take:
• MAOIs (must not be combined)
• Oral contraceptives (topiramate may reduce effectiveness)
• Anticonvulsants
• CNS depressants such as alcohol, benzodiazepines, or opioids
• Carbonic anhydrase inhibitors
• Blood pressure medications
• Diabetes medications

Common Side Effects
Dry mouth, constipation, insomnia, tingling in hands or feet, dizziness, altered taste, mood changes, fatigue, difficulty concentrating, or increased heart rate.

Serious Side Effects
Severe mood or behavior changes, suicidal thoughts, vision changes, eye pain, chest pain, irregular heartbeat, fainting, severe metabolic acidosis, kidney stones, or severe allergic reaction. Seek medical care immediately if these occur.

Pregnancy and Contraception
This medication is contraindicated in pregnancy due to risk of birth defects such as cleft lip and cleft palate. Individuals who can become pregnant must use effective contraception and require regular pregnancy testing. Do not use while breastfeeding.

Special Populations
• Not recommended for individuals under 18 except under specialist guidance
• Older adults may have higher risk of CNS and cardiovascular side effects
• Individuals with kidney or liver impairment may require dose adjustments
• Individuals with mental health disorders require close mood monitoring

Administration
Take orally once daily in the morning to reduce insomnia risk. Do not crush or split capsules. Do not abruptly discontinue; tapering may be required to prevent seizures.

Storage
Store at room temperature away from heat and moisture. Keep out of reach of children and pets.

Monitoring
Clinician may monitor blood pressure, heart rate, mood changes, pregnancy status, electrolytes, serum bicarbonate, kidney function, and weight trends. Regular follow-up is recommended.

Regulatory Note
Qsymia is FDA-approved. Compounded phentermine and topiramate are not FDA-approved and may vary in formulation. Off-label compounded use has not been reviewed by the FDA for safety, purity, or effectiveness.

L-Carnitine (Injectable)

Overview
Injectable L-carnitine is used for metabolic support, fat oxidation, exercise recovery, and mitochondrial function. FDA-approved L-carnitine products exist only for specific medical conditions such as primary or secondary carnitine deficiency. Compounded injectable L-carnitine for weight loss or wellness is not FDA-approved, and human safety data for these uses are limited.

Do Not Use If
• You have had a serious allergic reaction to L-carnitine or injectable vitamin formulations
• You have a seizure disorder that is not well controlled
• You have a known intolerance to injection additives or preservatives
• You are pregnant or breastfeeding
• You are under 18 years old

Precautions
Tell your clinician if you have:
• Seizure history (L-carnitine may lower seizure threshold in some individuals)
• Kidney or liver impairment
• Cardiovascular disease or arrhythmias
• Diabetes or glucose instability
• Fish allergies (rare cross-reactivity reported)
• History of GI disorders or chronic nausea
• Use of anticoagulants or antiplatelet medications

Drug Interactions
Inform your clinician if you take:
• Warfarin or other anticoagulants
• Thyroid hormone replacement
• Seizure medications
• Blood pressure medications
• Other injectable amino acids or metabolic therapies

Common Side Effects
Injection site redness or discomfort, nausea, stomach upset, fishy body odor, mild headache, restlessness, or diarrhea.

Serious Side Effects
Severe allergic reaction, worsening seizures, chest pain, difficulty breathing, swelling of face or throat, or severe GI distress. Seek urgent care if these occur.

Pregnancy and Contraception
Do not use injectable L-carnitine during pregnancy or breastfeeding unless specifically prescribed for a medical deficiency. Safety for wellness or weight-loss use is not established. Individuals who can become pregnant should notify their clinician if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Use caution in older adults due to possible cardiovascular sensitivity
• Individuals with seizure disorders may require close monitoring
• Individuals with kidney impairment may have altered clearance

Administration
Administer via intramuscular or slow subcutaneous injection. Follow clinician guidance on dose and frequency. Rotate injection sites. Do not mix with other injectables unless instructed.

Storage
Store according to pharmacy instructions, typically refrigerated or at room temperature depending on formulation. Do not use if discolored, cloudy, or expired.

Monitoring
Clinician may monitor kidney function, seizure stability, energy levels, GI tolerance, and any changes in blood glucose. Report any neurologic symptoms promptly.

Regulatory Note
Compounded injectable L-carnitine for weight loss or performance enhancement is not FDA-approved. Safety, purity, and efficacy have not been reviewed by the FDA.

Berberine

Overview
Berberine is a plant-derived alkaloid used for metabolic support, blood sugar regulation, cholesterol improvement, and general wellness. It is not FDA-approved for weight loss or metabolic disorders. Berberine affects glucose metabolism, gut microbiota, and liver enzymes. It may interact with multiple medications and can significantly alter blood sugar levels, liver function, and gastrointestinal activity.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have had a severe allergic reaction to berberine or related botanical compounds
• You have low blood pressure or episodes of fainting
• You have active liver disease unless cleared by your clinician
• You are taking cyclosporine (berberine can increase levels to dangerous ranges)

Precautions
Tell your clinician if you have:
• Diabetes, prediabetes, or episodes of low blood sugar
• Cardiovascular disease, arrhythmias, or low blood pressure
• Liver disease or a history of elevated liver enzymes
• Kidney impairment
• GI disorders such as IBS, IBD, or chronic constipation
• History of depression or use of serotonergic medications
• History of gallbladder disease
• Prior reactions to botanical supplements
• Use of alcohol, recreational substances, or stimulant-containing supplements

Drug Interactions
Berberine has strong interaction potential. Inform your clinician if you take:
• Metformin, insulin, or sulfonylureas
• Blood pressure medications
• Anticoagulants or antiplatelets
• Statins or cholesterol medications
• Thyroid medication
• Antidepressants or serotonergic agents
• Immunosuppressants (especially cyclosporine)
• Benzodiazepines or sedatives
• Antibiotics
• Any supplements affecting liver enzymes (turmeric, milk thistle, St. John’s Wort)

Common Side Effects
Nausea, diarrhea, constipation, stomach cramps, bloating, gas, headache, dizziness, or mild drop in blood sugar.

Serious Side Effects
Severe hypoglycemia, yellowing of skin or eyes, dark urine, severe abdominal pain, persistent vomiting, irregular heartbeat, fainting, severe allergic reaction, or symptoms of liver injury. Seek medical care immediately if serious symptoms occur.

Pregnancy and Contraception
Berberine is contraindicated in pregnancy and breastfeeding because it may affect fetal development and bilirubin metabolism in newborns. Individuals who can become pregnant should use effective contraception and notify their clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Older adults may be more prone to low blood pressure or GI side effects
• Individuals with diabetes require close monitoring for low blood sugar
• Avoid use in active liver disease unless monitored
• Use caution with kidney impairment
• Avoid use with significant cardiovascular instability or arrhythmias

Administration
Taken orally in capsule or tablet form with meals to reduce GI discomfort. Do not exceed clinician-recommended dosing. Do not combine with other blood sugar lowering supplements unless approved.

Storage
Store at room temperature in a dry place away from heat, light, and moisture. Keep out of reach of children and pets.

Monitoring
Clinician may monitor fasting glucose, A1c, liver enzymes, kidney function, blood pressure, cholesterol markers, and any GI or cardiovascular symptoms.

Regulatory Note
Berberine is not FDA-approved for any metabolic or weight-loss indication. Compounded or supplement forms are not reviewed by the FDA for safety, purity, or effectiveness.

Metformin

Overview
Metformin is an FDA-approved medication for type 2 diabetes. It improves insulin sensitivity, reduces liver glucose production, and may support weight loss and metabolic health. When prescribed for weight management or insulin resistance without diabetes, this use is off-label. Gastrointestinal effects are common, and rare but serious risks such as lactic acidosis can occur, especially in individuals with kidney, liver, or cardiovascular disease.

Do Not Use If
• You have severe kidney impairment
• You have active or severe liver disease
• You have unstable heart failure or severe cardiovascular instability
• You have a history of lactic acidosis
• You have severe dehydration or active alcohol misuse
• You are pregnant or breastfeeding unless specifically instructed by your clinician
• You are undergoing imaging that uses iodinated contrast without appropriate hold time
• You have had a severe allergic reaction to metformin

Precautions
Tell your clinician if you have:
• Diabetes, prediabetes, or hypoglycemia history
• Kidney or liver impairment
• Cardiovascular disease or heart failure
• Chronic alcohol use or binge drinking
• GI disorders such as IBS, IBD, or chronic nausea
• Vitamin B12 deficiency or anemia
• Thyroid disorders
• Any planned surgery or procedure requiring anesthesia
• Use of multiple medications that affect kidney function

Drug Interactions
Inform your clinician if you take:
• Insulin or sulfonylureas
• Diuretics
• Corticosteroids
• Thyroid hormone
• Blood pressure medications
• Contrast dye for imaging procedures
• Alcohol or medications affecting liver enzymes
• Other medications cleared by the kidneys
• Vitamin B12 supplements or medications that influence B12 levels

Common Side Effects
Nausea, diarrhea, gas, stomach discomfort, reduced appetite, metallic taste, fatigue, or mild headache. GI side effects often improve over time or with extended-release formulations.

Serious Side Effects
Lactic acidosis is rare but serious. Symptoms include severe fatigue, muscle pain, difficulty breathing, dizziness, irregular heartbeat, abdominal pain, or feeling cold. Other serious risks include dehydration, kidney injury, severe vomiting or diarrhea, or significant B12 deficiency. Seek medical care immediately for concerning symptoms.

Pregnancy and Contraception
Metformin may be used during pregnancy only under specific clinical guidance for conditions such as PCOS or gestational diabetes. For weight loss or metabolic use, pregnancy should be avoided unless approved by your clinician. Notify your clinician immediately if pregnancy occurs.

Special Populations
• Older adults may have increased risk of kidney-related issues
• Individuals with kidney or liver disease require close monitoring
• Individuals with alcohol use should avoid due to lactic acidosis risk
• Individuals with B12 deficiency require periodic monitoring
• Not recommended in those with acute illness causing dehydration

Administration
Take orally with meals to reduce GI discomfort. Do not crush extended-release tablets. Do not adjust your dose without clinician approval. Your clinician may recommend starting low and increasing gradually.

Storage
Store at room temperature away from moisture and heat. Keep out of reach of children and pets.

Monitoring
Clinician may monitor fasting glucose, A1c, kidney function, liver enzymes, vitamin B12 levels, and any symptoms suggestive of lactic acidosis or dehydration.

Regulatory Note
Metformin is FDA-approved for type 2 diabetes. All other uses, including weight management or metabolic optimization, are off-label. Compounded metformin formulations are not FDA-reviewed for safety, purity, or effectiveness.

GHRP-2 / GHRP-6

Overview
GHRP-2 and GHRP-6 are synthetic growth hormone-releasing peptides that stimulate endogenous growth hormone release. They are used in compounded formulations for anti-aging, wellness, body composition, or performance purposes. These peptides are not FDA-approved for any indication. Human safety data are limited, and long-term effects are not well established.

Do Not Use If

• Active cancer or history of cancer without oncology clearance
  
  
• Pregnant, planning pregnancy, or breastfeeding
  
  
• Known hypersensitivity to GHRP-2, GHRP-6, or formulation ingredients
  
  
• Under 18 years old
  
  

Precautions
Tell your clinician if you have:

• Diabetes, prediabetes, or metabolic syndrome
  
  
• Cardiovascular disease, hypertension, or edema
  
  
• Thyroid disorders
  
  
• Liver or kidney impairment
  
  
• Sleep apnea
  
  
• History of migraines or intracranial pressure issues
  
  
• Autoimmune disorders or immunosuppression
  
  
• Use of other GH-axis therapies (GH, GHRHs, other GHRPs)
  
  

Drug Interactions

• Antidiabetic medications may require adjustments
  
  
• Corticosteroids may blunt GH response
  
  
• Other GH-axis therapies may increase IGF-1 activity and side effect risk
  
  
• Alcohol may worsen metabolic or cardiovascular effects
  
  

Common Side Effects
Injection site irritation, mild flushing, headache, fatigue, mild edema, tingling in extremities, increased appetite (more pronounced with GHRP-6).

Serious Side Effects
Severe allergic reaction, rapid swelling, shortness of breath, significant blood sugar changes, persistent headaches with vision changes, fluid retention, or signs suggestive of tumor activity in individuals with prior cancer history.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Use effective contraception if capable of becoming pregnant. Notify clinician immediately if pregnancy occurs.

Special Populations

• Not recommended for individuals under 18
  
  
• Older adults may have higher risk of edema, glucose changes, or carpal tunnel symptoms
  
  
• Individuals with diabetes or prediabetes require close monitoring
  
  
• Avoid in individuals with a history of cancer unless cleared by oncology
  
  
• Use caution with kidney or liver impairment
  
  

Administration
Inject subcutaneously into abdomen, thigh, or upper arm. Follow dosing and rotation guidance provided by your clinician. Do not self-adjust dose.

Storage
Refrigerate at 36–46°F. Protect from light. Follow pharmacy instructions regarding reconstitution and beyond-use dates. Do not use if cloudy, discolored, or containing particles.

Monitoring
Clinician may monitor fasting glucose, A1c, IGF-1 levels, weight, blood pressure, fluid status, symptoms of nerve compression, headaches, or vision changes.

Regulatory Note
GHRP-2 and GHRP-6 are not FDA-approved. All human use is compounded and investigational. Safety and effectiveness have not been reviewed by the FDA.

Ibutamoren (MK-677)

Overview
Ibutamoren, also known as MK-677, is an investigational, orally active growth hormone secretagogue. It stimulates the pituitary gland to release growth hormone and increases IGF-1 levels. MK-677 is not FDA-approved for any indication. Human safety data, especially long-term effects, are limited. It is commonly used in compounded form for wellness, anti-aging, body composition, or recovery purposes.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have active cancer or a history of cancer without oncology clearance
• You have had a severe allergic reaction to MK-677 or any formulation ingredients
• You have uncontrolled diabetes or significant insulin resistance
• You have pituitary or hypothalamic tumors or disorders

Precautions
Tell your clinician if you have:
• Diabetes, prediabetes, or glucose intolerance
• Cardiovascular disease, hypertension, or edema
• Thyroid disorders
• Sleep apnea
• History of migraines, vision changes, or intracranial pressure issues
• Kidney or liver impairment
• Autoimmune disorders or chronic inflammatory conditions
• Prior history of cancer
• Use of corticosteroids, growth hormone therapies, or other GH/IGF-1 stimulating agents
• Medications affecting metabolism, appetite, or cardiac function

Drug Interactions
Inform your clinician if you take:
• Insulin or oral antidiabetics
• Corticosteroids
• Thyroid medications
• Growth hormone, GHRH, GHRP, or other IGF-1 affecting peptides
• Blood pressure medications
• Alcohol or sedatives
• Appetite stimulants, weight-gain compounds, or investigational peptides

Common Side Effects
Increased appetite, mild edema or fluid retention, fatigue, transient headache, joint stiffness, muscle aches, tingling in extremities, or mild injection-site irritation (if injectable compounded formulation).

Serious Side Effects
Severe allergic reaction, rapid or unexplained swelling, significant edema, worsening insulin resistance or blood sugar control, persistent headache with vision changes, chest pain, shortness of breath, or symptoms suggesting tumor activity in individuals with prior cancer history.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception while taking MK-677. Notify your clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Older adults may be at higher risk for edema, insulin resistance, or joint pain
• Individuals with diabetes require close glucose monitoring
• Use caution in kidney or liver impairment
• Avoid in individuals with a history of cancer unless cleared by oncology

Administration
Taken orally (capsule or liquid) once daily as prescribed by your clinician. Follow exact dosing instructions and do not self-adjust.

Storage
Store according to pharmacy instructions, typically refrigerated or at room temperature away from light and moisture. Do not use if solution is cloudy, discolored, or past beyond-use date.

Monitoring
Clinician may monitor fasting glucose, A1c, IGF-1 levels, weight, edema, appetite, blood pressure, joint and muscle discomfort, and any vision or neurologic changes. Individuals with prior cancer history may require additional surveillance.

Regulatory Note
MK-677 is not FDA-approved. All use is compounded, investigational, and off-label. Safety, purity, and efficacy have not been reviewed by the FDA.

Glutathione

Overview
Glutathione is a naturally occurring tripeptide composed of glutamine, cysteine, and glycine. It acts as a key intracellular antioxidant. Injectable glutathione is commonly used for antioxidant support, detoxification, and skin wellness purposes. Glutathione injections are not FDA-approved for any of these uses. Long-term safety and efficacy data are limited, and all use is considered investigational or off-label.

Do Not Use If

• You are pregnant, planning pregnancy, or breastfeeding
  
  
• You are under 18 years old
  
  
• You have a known allergy to glutathione or any formulation ingredients
  
  
• You have active cancer or a history of cancer without oncology clearance
  
  

Precautions / Tell Your Clinician If You Have

• Liver or kidney impairment
  
  
• Autoimmune disorders or chronic inflammatory conditions
  
  
• Cardiovascular disease, uncontrolled hypertension, or edema
  
  
• History of seizures, migraines, or neurologic disorders
  
  
• History of hypersensitivity to other antioxidants or thiol compounds
  
  
• Concurrent use of other investigational therapies or injectable supplements
  
  

Drug Interactions

• Anticoagulants or antiplatelet medications (theoretical interaction with oxidative balance)
  
  
• Chemotherapy agents (may affect redox status)
  
  
• Other antioxidant or metabolic injections
  
  
• Medications affecting liver metabolism or glutathione pathways
  
  

Common Side Effects
Injection site redness, mild pain, transient swelling, mild fatigue, temporary dizziness, or mild headache

Serious Side Effects (Seek Medical Attention Immediately)
Severe allergic reaction, sudden swelling, shortness of breath, severe dizziness, chest pain, or neurologic changes. Seek urgent care if these occur.

Pregnancy & Contraception
Do not use during pregnancy or breastfeeding unless specifically authorized by a clinician. Individuals who can become pregnant should use effective contraception. Notify your clinician immediately if pregnancy occurs.

Special Populations

• Pediatrics (<18 years): Not recommended
  
  
• Older adults: May be more sensitive to injection-related effects or mild hypotension
  
  
• Individuals with kidney or liver impairment: Use caution
  
  
• Individuals with cancer history: Avoid unless cleared by oncology
  
  

Administration
Administer via subcutaneous or slow intravenous injection as directed by a licensed clinician. Rotate injection sites if applicable. Follow exact dosing schedule and do not self-adjust.

Storage
Store refrigerated at 36–46°F (2–8°C). Protect from light. Do not use if solution is cloudy, discolored, or contains particulates.

Monitoring
Clinician may monitor liver and kidney function, blood pressure, metabolic markers, injection site reactions, and any unexpected adverse effects.

Regulatory Note
Injectable glutathione is not FDA-approved. All human use is considered investigational and compounded formulations may vary in quality, potency, and sterility. The FDA has not reviewed these products for safety or effectiveness.

GHK-Cu

Overview
GHK-Cu is a naturally occurring copper peptide involved in tissue repair, collagen synthesis, and anti-inflammatory signaling. Injectable or topical GHK-Cu is commonly used for skin health, wound healing, hair restoration, and regenerative purposes. GHK-Cu is not FDA-approved for any of these uses. Human clinical data for these applications are limited, and all use is investigational or off-label.

Do Not Use If

• You are pregnant, planning pregnancy, or breastfeeding
  
  
• You are under 18 years old
  
  
• You have active cancer or a history of cancer without oncology clearance
  
  
• You have known copper metabolism disorders (e.g., Wilson’s disease)
  
  
• You have had a severe allergic reaction to GHK-Cu or formulation components
  
  

Precautions / Tell Your Clinician If You Have

• Liver or kidney impairment
  
  
• Cardiovascular disease or hypertension
  
  
• Autoimmune disorders or chronic inflammatory conditions
  
  
• History of hypersensitivity reactions to peptides or metal-based compounds
  
  
• Use of other investigational peptides, topical agents, or regenerative therapies
  
  
• Skin conditions that may interfere with absorption if using topical formulations
  
  

Drug Interactions

• Anticoagulants or antiplatelet medications (theoretical interaction with tissue repair pathways)
  
  
• Immunosuppressants (may alter peptide effectiveness)
  
  
• Other regenerative peptides or biologics
  
  
• Topical copper or metal-containing compounds
  
  

Common Side Effects
Injection or topical site redness, mild swelling, transient tingling, mild irritation, temporary flushing, or mild headache

Serious Side Effects (Seek Medical Attention Immediately)
Severe allergic reaction, rapid or significant swelling, chest pain, difficulty breathing, severe dizziness, or neurologic changes. Seek urgent care if these occur.

Pregnancy & Contraception
Do not use during pregnancy or breastfeeding unless specifically authorized by a clinician. Individuals who can become pregnant should use effective contraception. Notify your clinician immediately if pregnancy occurs.

Special Populations

• Pediatrics (<18 years): Not recommended
  
  
• Older adults: May be more sensitive to injection or topical effects
  
  
• Individuals with liver or kidney impairment: Use caution
  
  
• Individuals with cancer history: Avoid unless cleared by oncology
  
  

Administration
Administer via subcutaneous injection or topical application as directed by a licensed clinician. Rotate injection sites if applicable. Follow the dosing schedule exactly and do not self-adjust.

Storage
Refrigerate at 36–46°F (2–8°C). Protect from light. Do not use if the solution is cloudy, discolored, or contains particulates.

Monitoring
Clinician may monitor liver and kidney function, blood pressure, skin and injection site reactions, and any unexpected adverse effects.

Regulatory Note
GHK-Cu is not FDA-approved. All human use is considered investigational and compounded formulations may vary in quality, potency, and sterility. The FDA has not reviewed these products for safety or effectiveness.

KPV

Overview
KPV is a tripeptide derived from the alpha-melanocyte stimulating hormone (α-MSH) and is used for its anti-inflammatory and tissue-repair properties. It is commonly compounded for skin health, wound healing, and inflammation modulation. KPV is not FDA-approved for any indication. Human clinical data are limited, and all use is investigational or off-label.

Do Not Use If

• You are pregnant, planning pregnancy, or breastfeeding
  
  
• You are under 18 years old
  
  
• You have active cancer or a history of cancer without oncology clearance
  
  
• You have had a severe allergic reaction to KPV or formulation ingredients
  
  

Precautions / Tell Your Clinician If You Have

• Autoimmune or inflammatory disorders
  
  
• Cardiovascular disease or hypertension
  
  
• Liver or kidney impairment
  
  
• Skin conditions that may interfere with absorption if topical formulations are used
  
  
• Use of other investigational peptides, biologics, or regenerative therapies
  
  

Drug Interactions

• Immunosuppressants (may alter peptide effectiveness)
  
  
• Other regenerative peptides or biologics
  
  
• Topical anti-inflammatory or metal-containing compounds
  
  

Common Side Effects
Mild redness, irritation, tingling, temporary itching, mild swelling, or transient headache at the application or injection site

Serious Side Effects (Seek Medical Attention Immediately)
Severe allergic reaction, rapid swelling, chest pain, shortness of breath, significant dizziness, or neurologic symptoms. Seek urgent care if these occur.

Pregnancy & Contraception
Do not use during pregnancy or breastfeeding unless specifically authorized by a clinician. Individuals who can become pregnant should use effective contraception. Notify your clinician immediately if pregnancy occurs.

Special Populations

• Pediatrics (<18 years): Not recommended
  
  
• Older adults: May be more sensitive to injection or topical effects
  
  
• Individuals with liver or kidney impairment: Use caution
  
  
• Individuals with cancer history: Avoid unless cleared by oncology
  
  

Administration
Administer subcutaneously or topically as directed by a licensed clinician. Rotate injection sites if applicable. Follow the dosing schedule exactly; do not self-adjust.

Storage
Refrigerate at 36–46°F (2–8°C). Protect from light. Do not use if the solution is cloudy, discolored, or contains particulates.

Monitoring
Clinician may monitor injection site or skin reactions, liver and kidney function, inflammatory markers, and any unexpected adverse effects.

Regulatory Note
KPV is not FDA-approved. All use is compounded and investigational. The FDA has not evaluated these formulations for safety, purity, or effectiveness.

Epitalon

Overview
Epitalon is a synthetic tetrapeptide used for anti-aging, cellular longevity, and wellness purposes. It is not FDA-approved for any indication. Human clinical data are limited, and long-term safety has not been established. All use is considered investigational and compounded formulations may vary in quality, sterility, and potency.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have active cancer or a history of cancer without oncology clearance
• You have had a severe allergic reaction to Epitalon or formulation components

Precautions
Tell your clinician if you have:
• Cardiovascular disease, hypertension, or edema
• Thyroid or endocrine disorders
• Liver or kidney impairment
• Autoimmune conditions or immunosuppression
• History of neurologic conditions or chronic headaches
• Any history of cancer or precancerous lesions
• Concurrent use of other peptides or investigational therapies

Drug Interactions
Human data on drug interactions are limited. Disclose all medications and supplements to your clinician, especially:
• Anticoagulants or antiplatelet drugs
• Immunosuppressants
• Corticosteroids
• Other investigational peptides

Common Side Effects
Injection site redness or irritation, mild headache, temporary fatigue, dizziness, nausea, or transient sleep disturbances.

Serious Side Effects
Severe allergic reaction, chest pain, shortness of breath, rapid swelling, severe dizziness, or neurologic changes. Seek immediate medical care if these occur.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception and notify their clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Use caution in older adults
• Avoid in individuals with a history of cancer unless cleared by oncology
• Use caution in liver or kidney impairment

Administration
Administer subcutaneously into the abdomen, thigh, or upper arm as directed by your clinician. Rotate injection sites. Do not adjust dose independently.

Storage
Refrigerate at 36–46°F (2–8°C). Protect from light. Follow pharmacy instructions for reconstitution and beyond-use dates. Do not use if cloudy, discolored, or containing particles.

Monitoring
Clinician may monitor fasting glucose, blood pressure, weight, liver and kidney function, and any neurologic or vascular symptoms. Individuals with a history of cancer may require additional surveillance.

Regulatory Note
Epitalon is not FDA-approved. It is available only through compounded investigational products. Safety, purity, and effectiveness have not been reviewed by the FDA.

Thymalin

Overview
Thymalin is a synthetic peptide derived from thymic extracts, used for immune support, cellular health, and anti-aging purposes. It is not FDA-approved for any indication. Human clinical data are limited, and long-term safety has not been established. All use is considered investigational and compounded formulations may vary in quality, sterility, and potency.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have active cancer or a history of cancer without oncology clearance
• You have had a severe allergic reaction to Thymalin or any component of the formulation

Precautions
Tell your clinician if you have:
• Autoimmune disorders or immunosuppression
• Cardiovascular disease, hypertension, or edema
• Liver or kidney impairment
• History of neurologic or endocrine disorders
• Any history of cancer or precancerous lesions
• Concurrent use of other peptides or immunomodulatory therapies

Drug Interactions
Human data on drug interactions are limited. Disclose all medications and supplements to your clinician, especially:
• Immunosuppressants
• Corticosteroids
• Other investigational peptides

Common Side Effects
Injection site redness or irritation, mild headache, transient fatigue, dizziness, or mild flu-like symptoms.

Serious Side Effects
Severe allergic reaction, chest pain, shortness of breath, rapid swelling, severe dizziness, or neurologic changes. Seek immediate medical care if these occur.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception and notify their clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Use caution in older adults
• Avoid in individuals with a history of cancer unless cleared by oncology
• Use caution in liver or kidney impairment

Administration
Administer subcutaneously into the abdomen, thigh, or upper arm as directed by your clinician. Rotate injection sites. Do not adjust dose independently.

Storage
Refrigerate at 36–46°F (2–8°C). Protect from light. Follow pharmacy instructions for reconstitution and beyond-use dates. Do not use if cloudy, discolored, or containing particles.

Monitoring
Clinician may monitor immune markers, blood counts, liver and kidney function, weight, and any neurologic or vascular symptoms. Individuals with a history of cancer may require additional surveillance.

Regulatory Note
Thymalin is not FDA-approved. It is available only through compounded investigational products. Safety, purity, and effectiveness have not been reviewed by the FDA.

Collagen Peptide

Overview
Collagen peptides are short-chain amino acid fragments derived from animal or marine collagen. They are commonly used for skin, joint, hair, nail, and connective tissue support. Injectable or compounded formulations are not FDA-approved for any specific indication. Human clinical data are limited, and long-term safety is not fully established. Use is considered investigational.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have had a severe allergic reaction to collagen or formulation ingredients
• You have known allergies to bovine, porcine, or marine proteins used in the product

Precautions
Tell your clinician if you have:
• Autoimmune or inflammatory disorders
• Cardiovascular disease, hypertension, or edema
• Liver or kidney impairment
• History of gastrointestinal disorders
• History of allergic reactions to proteins or supplements
• Concurrent use of other investigational peptides or biologics

Drug Interactions
Limited data available. Disclose all medications, supplements, and biologics to your clinician, especially:
• Immunosuppressants
• Other injectable peptides or amino acid therapies
• Anticoagulants or antiplatelet medications

Common Side Effects
Injection site redness or irritation, mild swelling, transient headache, mild nausea, or temporary fatigue.

Serious Side Effects
Severe allergic reaction, rapid swelling, chest pain, shortness of breath, dizziness, or unusual neurologic or vascular symptoms. Seek immediate medical attention if these occur.

Pregnancy and Contraception
Not recommended during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception while receiving collagen peptides and notify their clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Use caution in older adults due to potential vascular or renal changes
• Use caution in patients with allergies to source proteins
• Avoid in individuals with a history of cancer unless cleared by oncology
• Use caution in kidney or liver impairment

Administration
Administer subcutaneously or intramuscularly as directed by your clinician. Rotate injection sites. Follow the dosing instructions precisely and do not adjust the dose independently.

Storage
Refrigerate at 36–46°F (2–8°C). Protect from light. Follow pharmacy instructions for reconstitution and beyond-use dates. Do not use if the solution is cloudy, discolored, or contains particles.

Monitoring
Clinician may monitor skin, hair, and nail improvements, joint function, inflammation markers, kidney and liver function, and any injection site reactions. Individuals with prior allergies may require more frequent observation.

Regulatory Note
Collagen peptides are not FDA-approved for injectable or compounded use. Safety, purity, and effectiveness have not been reviewed by the FDA.

Vitamin C (Injectable)

Overview
Injectable vitamin C (ascorbic acid) is used for antioxidant support, immune support, skin health, collagen synthesis, and overall wellness. While oral vitamin C is widely used and generally considered safe, injectable forms are not FDA-approved for wellness or performance purposes. Human safety data for high-dose or compounded injectable forms are limited, and long-term effects are not fully established. Use is considered investigational.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have a history of severe allergic reaction to vitamin C or injectable formulations
• You have glucose-6-phosphate dehydrogenase (G6PD) deficiency
• You have a history of kidney stones or severe renal impairment
• You have active cancer unless cleared by oncology

Precautions
Tell your clinician if you have:
• Kidney or liver impairment
• Cardiovascular disease or hypertension
• Diabetes or glucose regulation issues
• History of oxalate kidney stones
• Iron overload disorders (risk of increased iron absorption)
• History of allergic reactions to injectable vitamins or supplements
• Concurrent use of other intravenous therapies or antioxidants

Drug Interactions
• Oral or injectable iron supplements → may increase iron absorption
• Anticoagulants or antiplatelet agents → monitor coagulation
• Chemotherapy agents → discuss timing and interactions with oncology team
• Other injectable vitamins or antioxidants → potential additive effects

Common Side Effects
Injection site irritation, mild redness, warmth, transient headache, mild nausea, or temporary fatigue.

Serious Side Effects
Severe allergic reaction, rapid swelling, chest pain, shortness of breath, dizziness, severe nausea, or signs of kidney stress. Seek immediate medical care if these occur.

Pregnancy and Contraception
Not recommended during pregnancy or breastfeeding unless specifically directed by a clinician. Individuals who can become pregnant should use effective contraception and notify their clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Older adults may be more sensitive to changes in kidney function or blood pressure
• Individuals with diabetes or kidney disease require close monitoring
• Avoid use in patients with history of kidney stones or iron overload unless approved by clinician
• Individuals with cancer should obtain oncology clearance

Administration
Administer via intravenous infusion, subcutaneous, or intramuscular injection as directed by a licensed clinician. Follow exact dosing schedule. Do not self-adjust.

Storage
Store according to pharmacy instructions, typically refrigerated at 36–46°F (2–8°C). Protect from light. Do not use if solution is cloudy, discolored, or contains particles.

Monitoring
Clinician may monitor renal function, blood glucose, cardiovascular status, injection site reactions, and overall tolerance. In patients with cancer or kidney disease, additional labs may be required.

Regulatory Note
Injectable vitamin C is not FDA-approved for wellness, performance, or anti-aging uses. Compounded formulations may vary by pharmacy, and safety, purity, and effectiveness have not been reviewed by the FDA.

Hyaluronic Acid (Injectable)

Overview
Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan found in connective tissues, skin, and synovial fluid. Injectable HA is used for joint support, skin hydration, anti-aging, tissue repair, and cosmetic purposes. These injections are not FDA-approved for systemic wellness or anti-aging. Compounded or off-label use is considered investigational. Human safety data for these applications are limited.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have a known hypersensitivity to hyaluronic acid or formulation excipients
• You have active infection at the injection site
• You have active cancer unless cleared by oncology
• You have history of severe allergic reaction to injectable therapies

Precautions
Tell your clinician if you have:
• Autoimmune disorders or chronic inflammatory conditions
• Bleeding disorders or are on anticoagulant therapy
• History of joint infection or prior joint replacement in the target area
• Skin conditions, eczema, or psoriasis at the injection site
• Liver or kidney impairment
• Use of other injectable or topical peptides or fillers

Drug Interactions
• Anticoagulants or antiplatelet medications → increased bleeding/bruising risk
• Immunosuppressants → potential increased infection risk
• Other injectable peptides, fillers, or biologics → additive effects unknown

Common Side Effects
Injection site redness, swelling, mild pain, warmth, itching, or temporary bruising. Mild transient discomfort in joints may occur with intra-articular injections.

Serious Side Effects
Severe allergic reaction, rapid swelling, joint pain, fever, infection at injection site, shortness of breath, or systemic hypersensitivity. Seek immediate medical care if these occur.

Pregnancy and Contraception
Not recommended during pregnancy or breastfeeding unless specifically directed by a clinician. Individuals who can become pregnant should use effective contraception and notify their clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Older adults may have increased sensitivity to joint or skin reactions
• Individuals with autoimmune disorders, bleeding risk, or prior joint replacement require close monitoring
• Avoid use in patients with active infection or cancer unless cleared by clinician

Administration
Administered via subcutaneous, intradermal, or intra-articular injection as directed by a licensed clinician. Follow exact dosing and injection technique provided. Rotate sites as instructed. Do not self-administer.

Storage
Store according to pharmacy instructions, typically refrigerated at 36–46°F (2–8°C). Protect from light. Do not use if solution is cloudy, discolored, or contains particles.

Monitoring
Clinician may monitor injection sites for infection, swelling, or allergic reactions. For intra-articular injections, monitor joint function, pain, and signs of inflammation.

Regulatory Note
Injectable hyaluronic acid is not FDA-approved for systemic wellness, anti-aging, or performance purposes. Compounded formulations vary by pharmacy. Safety, purity, and effectiveness have not been reviewed by the FDA.

TRT (Testosterone Replacement Therapy)

Overview
TRT is used to treat clinically diagnosed testosterone deficiency. It may be prescribed as injections, gels, patches, or subcutaneous pellets. TRT is FDA-approved for hypogonadism, but all wellness, anti-aging, or performance uses are considered off-label. Long-term safety depends on monitoring and individual health factors.

Do Not Use If
• You have prostate or breast cancer
• You have severe heart failure, uncontrolled hypertension, or recent cardiovascular events
• You have polycythemia (high red blood cell counts)
• You are pregnant or breastfeeding
• You have a history of severe allergic reaction to testosterone formulations

Precautions
Tell your clinician if you have:
• Cardiovascular disease, hypertension, or arrhythmias
• Sleep apnea
• Liver or kidney impairment
• History of blood clots
• Diabetes or metabolic syndrome
• History of prostate or breast disorders
• Prior abnormal PSA or digital rectal exam findings

Drug Interactions
• Anticoagulants → may alter bleeding risk
• Corticosteroids → may affect glucose metabolism
• Insulin or antidiabetic medications → monitor for changes in glycemic control
• Other hormones or anabolic steroids → additive effects

Common Side Effects
Injection site pain, mild swelling or redness, acne, increased hair growth, mood changes, mild fluid retention.

Serious Side Effects (Seek medical attention immediately)
Severe allergic reaction, chest pain, shortness of breath, sudden leg swelling (possible clot), polycythemia (fatigue, headache, dizziness), worsening cardiovascular symptoms, prostate enlargement or urinary obstruction, severe liver dysfunction.

Pregnancy and Contraception
Not recommended during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception and notify their clinician immediately if pregnancy occurs.

Special Populations
• Pediatrics: Not recommended
• Older adults: May have higher risk of cardiovascular, hematologic, or prostate effects
• Individuals with diabetes or metabolic syndrome: require close monitoring

Administration
Administer via intramuscular, subcutaneous injection, topical gel, or patch as directed by your clinician. Follow dosage schedule carefully. Do not self-adjust dose.

Storage
Follow pharmacy instructions; generally refrigerate injections or store gels and patches at room temperature as specified. Protect from light. Do not use if solution is cloudy or formulation is damaged.

Monitoring
Clinician may monitor testosterone levels, hematocrit, hemoglobin, liver function, lipid profile, PSA, digital rectal exams, blood pressure, cardiovascular health, and symptom response.

Regulatory Note
TRT is FDA-approved for hypogonadism. Use for performance enhancement, anti-aging, or general wellness is off-label. Compounded formulations may vary in potency and sterility; ensure pharmacy compliance with USP standards.

Thyroid Support

Overview
Thyroid support therapies include prescription thyroid hormone replacement (e.g., levothyroxine, liothyronine) and compounded formulations for hypothyroidism or subclinical thyroid disorders. These therapies are FDA-approved for diagnosed thyroid hormone deficiencies but are considered off-label for general wellness, weight loss, or anti-aging purposes. Proper dosing and monitoring are essential to avoid adverse effects.

Do Not Use If
• You have untreated adrenal insufficiency
• You have hypersensitivity to thyroid hormones or formulation ingredients
• You are pregnant or breastfeeding without clinician supervision
• You have acute myocardial infarction or severe cardiovascular disease

Precautions
Tell your clinician if you have:
• Heart disease, arrhythmias, or hypertension
• Diabetes or insulin resistance
• Osteoporosis
• History of thyroid nodules or malignancy
• Use of anticoagulants
• Gastrointestinal disorders affecting absorption

Drug Interactions
• Anticoagulants (e.g., warfarin) → may increase bleeding risk
• Insulin or oral antidiabetics → thyroid hormones can alter glucose metabolism
• Proton pump inhibitors, calcium, iron, or multivitamins → may impair absorption
• Other hormones or stimulants → additive cardiovascular effects

Common Side Effects
Palpitations, mild anxiety, tremor, sweating, heat intolerance, mild diarrhea, headache.

Serious Side Effects (Seek medical attention immediately)
Severe chest pain, irregular heartbeat, shortness of breath, significant blood pressure changes, severe hyperthyroidism symptoms (agitation, fever, confusion), allergic reaction.

Pregnancy and Contraception
Thyroid hormone therapy may be required during pregnancy for maternal or fetal health. Do not self-adjust doses. Women capable of pregnancy should consult their clinician regarding safe dosing and monitoring.

Special Populations
• Pediatrics: dosing requires careful endocrinology supervision
• Older adults: higher risk of cardiovascular and bone complications
• Individuals with cardiovascular disease: require close monitoring

Administration
Oral tablets, capsules, or compounded formulations as prescribed. Take on an empty stomach, typically in the morning. Avoid taking with interfering foods or supplements.

Storage
Store at room temperature away from heat and moisture. Protect from light. Do not use if tablets are damaged or discolored.

Monitoring
Clinician may monitor TSH, free T4, free T3, heart rate, blood pressure, symptom response, and bone density periodically.

Regulatory Note
Thyroid hormone replacement is FDA-approved for hypothyroidism and related conditions. Compounded or off-label use is not FDA-reviewed for safety, potency, or quality.

DHEA

Overview
DHEA (dehydroepiandrosterone) is a naturally occurring steroid hormone produced by the adrenal glands. It serves as a precursor to sex hormones, including estrogen and testosterone. Supplemental or compounded DHEA is used for hormonal support, adrenal function, mood, bone density, and general wellness. It is not FDA-approved for anti-aging or general wellness purposes, and long-term safety and efficacy have not been fully established.

Do Not Use If
• You have hormone-sensitive cancers (breast, prostate, ovarian)
• You have known hypersensitivity to DHEA or formulation ingredients
• You are pregnant, planning pregnancy, or breastfeeding without clinician supervision
• You have uncontrolled endocrine disorders

Precautions
Tell your clinician if you have:
• Cardiovascular disease, hypertension, or arrhythmias
• Liver or kidney impairment
• Diabetes or insulin resistance
• Mood disorders or psychiatric conditions
• Use of other hormone therapies or supplements

Drug Interactions
• Hormone therapies (estrogen, progesterone, testosterone, pregnenolone) → additive or interfering effects
• Corticosteroids → may alter adrenal axis
• Antidiabetic medications → may affect glucose metabolism
• Anticoagulants → monitor as steroidal hormones may impact clotting

Common Side Effects
Acne, oily skin, hair growth, mild mood changes, headache, fatigue, and slight changes in blood pressure.

Serious Side Effects (Seek medical attention immediately)
Severe hormone imbalances, uncontrolled hypertension, liver dysfunction, severe mood disturbances, allergic reaction, or symptoms of hormone-sensitive cancer progression.

Pregnancy and Contraception
Contraindicated during pregnancy and breastfeeding unless specifically approved by a clinician. Women capable of pregnancy should use reliable contraception and discuss therapy implications with their clinician.

Special Populations
• Pediatrics: not established; generally not recommended
• Older adults: may be more sensitive to hormonal fluctuations and cardiovascular effects
• Individuals with a history of cancer: use only under oncology clearance
• Individuals with metabolic or endocrine disorders require close monitoring

Administration
Oral capsules, sublingual tablets, or compounded formulations as prescribed. Follow exact dosing instructions provided by your clinician.

Storage
Store at room temperature, away from heat and moisture. Protect from light. Do not use if capsules or tablets are damaged, discolored, or expired.

Monitoring
Clinician may monitor hormone levels (DHEA, testosterone, estrogen), liver and kidney function, blood pressure, lipid profile, glucose, mood, and other clinical symptoms.

Regulatory Note
DHEA is not FDA-approved for anti-aging or general wellness. Compounded formulations vary by pharmacy and are not FDA-reviewed for safety, potency, or efficacy.

Pregnenolone

Overview
Pregnenolone is a naturally occurring steroid hormone produced by the adrenal glands and a precursor to progesterone, estrogen, and testosterone. Supplemental or compounded pregnenolone is used to support hormonal balance, cognitive function, mood, energy, and general wellness. It is not FDA-approved for anti-aging or general wellness purposes, and long-term safety and efficacy data are limited.

Do Not Use If
• You have hormone-sensitive cancers (breast, prostate, ovarian)
• You have known hypersensitivity to pregnenolone or formulation ingredients
• You are pregnant, planning pregnancy, or breastfeeding without clinician supervision
• You have uncontrolled endocrine disorders

Precautions
Tell your clinician if you have:
• Cardiovascular disease, hypertension, or arrhythmias
• Liver or kidney impairment
• Diabetes or insulin resistance
• Mood disorders or psychiatric conditions
• Use of other hormone therapies or supplements

Drug Interactions
• Hormone therapies (estrogen, progesterone, testosterone, DHEA) → additive or interfering effects
• Corticosteroids → may alter adrenal axis
• Antidiabetic medications → may affect glucose metabolism
• Anticoagulants → monitor as steroidal hormones may impact clotting

Common Side Effects
Headache, fatigue, mood changes, acne, hair changes, mild blood pressure fluctuations.

Serious Side Effects (Seek medical attention immediately)
Severe hormonal imbalance, uncontrolled hypertension, liver dysfunction, severe mood disturbances, allergic reaction, or symptoms of hormone-sensitive cancer progression.

Pregnancy and Contraception
Contraindicated during pregnancy and breastfeeding unless specifically approved by a clinician. Women capable of pregnancy should use reliable contraception and discuss therapy implications with their clinician.

Special Populations
• Pediatrics: not established; generally not recommended
• Older adults: may be more sensitive to hormonal fluctuations and cardiovascular effects
• Individuals with a history of cancer: use only under oncology clearance
• Individuals with metabolic or endocrine disorders require close monitoring

Administration
Oral capsules, sublingual tablets, or compounded formulations as prescribed. Follow exact dosing instructions provided by your clinician.

Storage
Store at room temperature, away from heat and moisture. Protect from light. Do not use if capsules or tablets are damaged, discolored, or expired.

Monitoring
Clinician may monitor hormone levels (pregnenolone, testosterone, estrogen, progesterone), liver and kidney function, blood pressure, glucose, mood, and other clinical symptoms.

Regulatory Note
Pregnenolone is not FDA-approved for anti-aging or general wellness. Compounded formulations vary by pharmacy and are not FDA-reviewed for safety, potency, or efficacy.

Vitamin B12 (Injectable)

Overview
Injectable vitamin B12 (commonly methylcobalamin or hydroxocobalamin) is used for energy support, metabolic function, and treatment of true B12 deficiency. Off-label uses include wellness, anti-aging, or performance enhancement. Injectable B12 is FDA-approved only for treating deficiency and certain anemias; other uses are investigational.

Do Not Use If
• You have had a severe allergic reaction to B12, cobalt, or injectable formulations
• You have Leber optic neuropathy or a related family history
• You are under 18 unless specifically prescribed for deficiency
• You have active cancer unless cleared by oncology

Precautions
Tell your clinician if you have:
• Cardiovascular disease or arrhythmias
• Kidney or liver impairment
• Skin conditions (acne, rosacea)
• Polycythemia or elevated red blood cell counts
• GI absorption issues
• Autoimmune or chronic inflammatory conditions
• Concurrent injections, vitamins, or metabolic therapies

Drug Interactions
Inform your clinician if you take:
• Metformin
• Proton pump inhibitors or H2 blockers
• Chloramphenicol
• Potassium supplements
• Other injectable vitamins or metabolic therapies
• Alcohol in significant amounts

Common Side Effects
Injection site redness or soreness, mild headache, nausea, diarrhea, flushing, transient increase in energy.

Serious Side Effects (Seek medical attention immediately)
Severe allergic reaction, rapid swelling, difficulty breathing, chest pain, irregular heartbeat, sudden dizziness, or worsening numbness/tingling.

Pregnancy and Contraception
Generally safe during pregnancy when indicated. For high-dose or off-label use, consult your clinician. Use effective contraception if capable of pregnancy.

Special Populations
• Children: only under medical supervision
• Older adults: monitor for anemia or deficiency markers
• Individuals with acne-prone skin: temporary flare-ups possible
• Individuals with cancer or kidney/liver issues: require clearance and monitoring

Administration
Administer intramuscularly or subcutaneously per clinician instructions. Rotate injection sites. Do not self-adjust dose or frequency.

Storage
Store at room temperature or as directed by pharmacy. Protect from excessive heat and light. Do not use if solution is cloudy or discolored.

Monitoring
Clinician may monitor B12 levels, methylmalonic acid, homocysteine, blood counts, and symptom response, especially for deficiency or metabolic support.

Regulatory Note
Only certain B12 injectables are FDA-approved for deficiency treatment. Wellness or performance uses are off-label, and compounded formulations are not FDA-reviewed.

Zinc Thymulin

Overview
Zinc Thymulin is a compounded injectable peptide combining zinc with thymulin, used for immune modulation, skin health, and cellular support. This therapy is not FDA-approved for any indication. Human safety and effectiveness data are limited, and all use is considered investigational.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have active cancer or a history of cancer without oncology clearance
• You have had a severe allergic reaction to zinc, thymulin, or injectable formulations

Precautions
Tell your clinician if you have:
• Kidney or liver impairment
• Cardiovascular disease, hypertension, or edema
• Autoimmune conditions or chronic inflammatory disorders
• History of GI disorders affecting absorption
• Any history of cancer or precancerous lesions
• Concurrent use of other mineral, peptide, or vitamin injections

Drug Interactions
Inform your clinician if you take:
• Chelating agents
• Immunosuppressants
• Other injectable peptides, vitamins, or minerals

Common Side Effects
Mild injection site redness or irritation, temporary nausea, mild headache, fatigue, or light dizziness

Serious Side Effects (Seek medical attention immediately)
Severe allergic reaction, rapid swelling, difficulty breathing, chest pain, irregular heartbeat, severe dizziness, or neurologic symptoms

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception while using this therapy. Notify your clinician immediately if pregnancy occurs.

Special Populations
Not recommended for individuals under 18. Older adults may be more sensitive to vascular or metabolic effects. Use caution with kidney or liver impairment. Avoid use in individuals with a history of cancer unless cleared by oncology.

Administration
Inject subcutaneously into the abdomen, thigh, or upper arm as directed by your clinician. Rotate injection sites to minimize irritation. Do not self-adjust dosing.

Storage
Refrigerate at 36–46°F (2–8°C) and protect from light. Follow pharmacy instructions for reconstitution and beyond-use dates. Do not use if solution is cloudy, discolored, or contains particles.

Monitoring
Clinician may monitor zinc and thymulin levels, immune markers, injection site reactions, and any unexpected adverse events. Individuals with cancer history may require ongoing surveillance.

Regulatory Note
Zinc Thymulin is not FDA-approved. All compounded formulations are investigational, and the FDA has not reviewed them for safety, purity, or effectiveness.

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PTD-DBM

Overview
PTD-DBM is a peptide-based compound used in skin and tissue regenerative applications. It is not FDA-approved for any indication. Human safety and effectiveness data are limited, and all use is considered investigational.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have active cancer or a history of cancer without oncology clearance
• You have had a severe allergic reaction to peptide products or formulation ingredients

Precautions
Tell your clinician if you have:
• Autoimmune disease or chronic inflammatory conditions
• Cardiovascular disease, hypertension, or edema
• Liver or kidney impairment
• History of clotting disorders
• Any prior reactions to regenerative peptides or biologics
• Use of other peptide or biologic therapies

Drug Interactions
Data are limited. Disclose all medications and supplements, especially:
• Anticoagulants or antiplatelet drugs
• Immunosuppressants
• Corticosteroids
• Other regenerative peptides or biologics

Common Side Effects
Injection site redness, mild swelling, temporary skin irritation, headache, fatigue, or transient nausea.

Serious Side Effects
Severe allergic reaction, rapid or unexplained swelling, chest pain, shortness of breath, significant dizziness, severe skin reactions. Seek immediate medical attention if these occur.

Pregnancy and Contraception
Do not use during pregnancy or breastfeeding. Individuals who can become pregnant should use effective contraception and notify their clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Older adults may be more sensitive to swelling or vascular changes
• Use caution in kidney or liver impairment
• Avoid use in individuals with a history of cancer unless cleared by oncology
• Use caution with clotting disorders

Administration
Inject subcutaneously into the targeted area or as directed by your clinician. Rotate injection sites to minimize irritation. Follow dosing instructions precisely. Do not self-adjust.

Storage
Refrigerate at 36–46°F (2–8°C). Protect from light. Follow pharmacy instructions regarding reconstitution and beyond-use dates. Do not use if solution is cloudy, discolored, or contains particles.

Monitoring
Clinician may monitor inflammatory markers, skin response, vascular status, injection site reactions, and any unexpected adverse effects. Cancer history may require ongoing surveillance.

Regulatory Note
PTD-DBM is not FDA-approved. This is a compounded, investigational product. Safety, purity, and effectiveness have not been reviewed by the FDA.

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Tranexamic Acid

Overview
Tranexamic acid is an antifibrinolytic agent used to reduce bleeding and improve wound healing, commonly used in cosmetic or aesthetic applications for skin brightening and scar reduction. All human use for skin and cosmetic purposes is off-label and investigational. Safety and effectiveness have not been reviewed by the FDA for these uses.

Do Not Use If
• You are pregnant, planning pregnancy, or breastfeeding
• You are under 18 years old
• You have active cancer unless cleared by oncology
• You have a history of thromboembolic events (e.g., DVT, PE, stroke)
• You have a known hypersensitivity to tranexamic acid or formulation ingredients

Precautions
Tell your clinician if you have:
• Cardiovascular disease, hypertension, or clotting disorders
• Kidney or liver impairment
• History of seizures or neurological disorders
• Autoimmune or chronic inflammatory conditions
• Use of anticoagulants or antiplatelet medications
• History of abnormal bleeding or bruising

Drug Interactions
Inform your clinician if you take:
• Anticoagulants (warfarin, DOACs)
• Antiplatelet medications (aspirin, clopidogrel)
• Hormonal therapies or oral contraceptives
• Other investigational or compounded skin/lightening agents

Common Side Effects
Mild redness, irritation, or burning at application or injection site; transient itching or mild swelling.

Serious Side Effects (Seek medical attention immediately)
Severe allergic reaction, swelling of face or throat, difficulty breathing, chest pain, sudden leg swelling, signs of clotting (pain, warmth, redness).

Pregnancy and Contraception
Not recommended during pregnancy or breastfeeding. Individuals capable of becoming pregnant should use effective contraception while using this therapy. Notify your clinician immediately if pregnancy occurs.

Special Populations
• Not recommended for individuals under 18
• Older adults may be at higher risk for vascular events
• Individuals with cardiovascular or kidney disease require close monitoring
• History of thromboembolic events requires clinician clearance

Administration
Applied topically or administered via subcutaneous injection as directed by your clinician. Follow the prescribed dose and rotation of sites. Do not self-adjust dose or frequency.

Storage
Store at 36–46°F (2–8°C) if injectable, or as directed by your pharmacy. Protect from light. Do not use if solution is cloudy, discolored, or contains particulates.

Monitoring
Clinician may monitor for skin response, vascular symptoms, blood pressure, kidney function, and signs of thromboembolic events.

Regulatory Note
Tranexamic acid is FDA-approved only for systemic control of bleeding. All cosmetic or aesthetic uses are compounded, investigational, and off-label. Safety, purity, and effectiveness for skin-related applications have not been reviewed by the FDA.